Knowledge-augmented AI agents for psychiatric drug safety info
Researchers built a multi-agent framework that integrates FDA adverse-event records, patient narratives from Reddit and WebMD, and a knowledge graph to help patients safely navigate antidepressant information online.
The system tracks provenance—distinguishing regulatory evidence from anecdotal experience—to prevent fear-amplification and nocebo responses that often trigger medication non-adherence in psychiatry.
Dataset covers 466,525 Reddit posts, 60,782 WebMD reviews, and twenty years of FDA records for nine antidepressants, with an LLM entity-recognition pipeline as the retrieval backbone.